version 6.1 release 12.1 Search Results


a foetidus cbs  (ATCC)
96
ATCC a foetidus cbs
A Foetidus Cbs, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/a foetidus cbs/product/ATCC
Average 96 stars, based on 1 article reviews
a foetidus cbs - by Bioz Stars, 2026-03
96/100 stars
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anti human cd163 rea406 pe  (Miltenyi Biotec)
91
Miltenyi Biotec anti human cd163 rea406 pe
Combination of CITE-seq, scRNA-seq, snRNA-seq, and spatial analyses enables generation of a human liver atlas and identification of bona fide human KCs, related to <xref ref-type=Figure 4 (A and B) Top DEGs (A) and DEPs (B) for the cell types from Figure 4 B. (C) Distinct profiles of cells or nuclei within the UMAP depending on isolation protocol used; 152,535 cells from ex vivo digestions and 15,063 nuclei. (D) Proportion of each cell type per patient profiled. (E) Proportion of indicated cell types as a % of total CD45 + cells calculated from ex vivo digested samples per surgery type. Ch; cholecystectomy, Re; resection, GB; gastric bypass. ∗ p < 0.05; one-way ANOVA with Bonferroni post-test. (F) Mapping of Visium UMAP zonation patterns onto tissue sections from patient H35 and H37. (G) Expression of indicated zonation genes in patients H35–H38 assessed by Molecular Cartography. (H and I) Expression of indicated proteins by MICS 100-plex protein analysis in the healthy (H) and steatotic (I) human liver. (J) Murine myeloid cells (cDC1s, cDC2s, Mig. cDCs, Macs, monocytes, and monocyte-derived cells; 42,922 cells) from mice fed the SD or WD for 24 or 36 weeks were isolated from Figure S5 J and re-clustered with TotalVI. (K) Distribution of cells in UMAP originating from SD- (purple) or WD- (yellow) fed mice. (L) Proportion of indicated cell types arising from mice fed the SD (purple) or WD (yellow). (M and N) Flow cytometry analysis of indicated cell populations in SD and WD-fed mice (24 weeks). Representative gating strategies (M) and absolute number of indicated populations (N). ∗ p < 0.05, ∗∗ p < 0.01 Student’s t test. Data are from 2 independent experiments with n = 5–6 per diet. (O and P) Top DEGs (O) and DEPs (P) for cell types from Figure 4 H. (Q) Top 25 Murine KC genes as expressed by the human myeloid cell clusters. (R) Mapping of KC signature onto Visium trajectory for healthy (purple) and steatotic (orange) livers. (S) Expression of VSIG4 mRNA within human myeloid cells. (T) Expression of VSIG4 (red) and CD163 (gray, top) or CD169 (gray, bottom) by MICS analysis in healthy human liver. (U) Representative images showing KC location (red) as assessed by MICS analysis in the healthy (left) and steatotic (right) human liver. PV, portal vein; CV, central Vein, dashed line indicates zones of steatosis. (V) Representative image of CD68 and CD163 staining in 10–15-year-old human liver paraffin sections. Image is representative of 6 different patients. (W) In silico gating strategy to isolate distinct myeloid cell populations identified from CITE-seq data. (X) Expression of VSIG4 and FOLR2 by live CD45 + cells also expressing CD14 in indicated human liver biopsies by flow cytometry. Data are representative of 21 biopsy samples analyzed. " width="250" height="auto" />
Anti Human Cd163 Rea406 Pe, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti human cd163 rea406 pe/product/Miltenyi Biotec
Average 91 stars, based on 1 article reviews
anti human cd163 rea406 pe - by Bioz Stars, 2026-03
91/100 stars
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administrative database/registry  (Disease Registry)
90
Disease Registry administrative database/registry
Combination of CITE-seq, scRNA-seq, snRNA-seq, and spatial analyses enables generation of a human liver atlas and identification of bona fide human KCs, related to <xref ref-type=Figure 4 (A and B) Top DEGs (A) and DEPs (B) for the cell types from Figure 4 B. (C) Distinct profiles of cells or nuclei within the UMAP depending on isolation protocol used; 152,535 cells from ex vivo digestions and 15,063 nuclei. (D) Proportion of each cell type per patient profiled. (E) Proportion of indicated cell types as a % of total CD45 + cells calculated from ex vivo digested samples per surgery type. Ch; cholecystectomy, Re; resection, GB; gastric bypass. ∗ p < 0.05; one-way ANOVA with Bonferroni post-test. (F) Mapping of Visium UMAP zonation patterns onto tissue sections from patient H35 and H37. (G) Expression of indicated zonation genes in patients H35–H38 assessed by Molecular Cartography. (H and I) Expression of indicated proteins by MICS 100-plex protein analysis in the healthy (H) and steatotic (I) human liver. (J) Murine myeloid cells (cDC1s, cDC2s, Mig. cDCs, Macs, monocytes, and monocyte-derived cells; 42,922 cells) from mice fed the SD or WD for 24 or 36 weeks were isolated from Figure S5 J and re-clustered with TotalVI. (K) Distribution of cells in UMAP originating from SD- (purple) or WD- (yellow) fed mice. (L) Proportion of indicated cell types arising from mice fed the SD (purple) or WD (yellow). (M and N) Flow cytometry analysis of indicated cell populations in SD and WD-fed mice (24 weeks). Representative gating strategies (M) and absolute number of indicated populations (N). ∗ p < 0.05, ∗∗ p < 0.01 Student’s t test. Data are from 2 independent experiments with n = 5–6 per diet. (O and P) Top DEGs (O) and DEPs (P) for cell types from Figure 4 H. (Q) Top 25 Murine KC genes as expressed by the human myeloid cell clusters. (R) Mapping of KC signature onto Visium trajectory for healthy (purple) and steatotic (orange) livers. (S) Expression of VSIG4 mRNA within human myeloid cells. (T) Expression of VSIG4 (red) and CD163 (gray, top) or CD169 (gray, bottom) by MICS analysis in healthy human liver. (U) Representative images showing KC location (red) as assessed by MICS analysis in the healthy (left) and steatotic (right) human liver. PV, portal vein; CV, central Vein, dashed line indicates zones of steatosis. (V) Representative image of CD68 and CD163 staining in 10–15-year-old human liver paraffin sections. Image is representative of 6 different patients. (W) In silico gating strategy to isolate distinct myeloid cell populations identified from CITE-seq data. (X) Expression of VSIG4 and FOLR2 by live CD45 + cells also expressing CD14 in indicated human liver biopsies by flow cytometry. Data are representative of 21 biopsy samples analyzed. " width="250" height="auto" />
Administrative Database/Registry, supplied by Disease Registry, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/administrative database/registry/product/Disease Registry
Average 90 stars, based on 1 article reviews
administrative database/registry - by Bioz Stars, 2026-03
90/100 stars
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nmr spectrometer bruker avance iv hd 400  (Bruker Corporation)
90
Bruker Corporation nmr spectrometer bruker avance iv hd 400
Combination of CITE-seq, scRNA-seq, snRNA-seq, and spatial analyses enables generation of a human liver atlas and identification of bona fide human KCs, related to <xref ref-type=Figure 4 (A and B) Top DEGs (A) and DEPs (B) for the cell types from Figure 4 B. (C) Distinct profiles of cells or nuclei within the UMAP depending on isolation protocol used; 152,535 cells from ex vivo digestions and 15,063 nuclei. (D) Proportion of each cell type per patient profiled. (E) Proportion of indicated cell types as a % of total CD45 + cells calculated from ex vivo digested samples per surgery type. Ch; cholecystectomy, Re; resection, GB; gastric bypass. ∗ p < 0.05; one-way ANOVA with Bonferroni post-test. (F) Mapping of Visium UMAP zonation patterns onto tissue sections from patient H35 and H37. (G) Expression of indicated zonation genes in patients H35–H38 assessed by Molecular Cartography. (H and I) Expression of indicated proteins by MICS 100-plex protein analysis in the healthy (H) and steatotic (I) human liver. (J) Murine myeloid cells (cDC1s, cDC2s, Mig. cDCs, Macs, monocytes, and monocyte-derived cells; 42,922 cells) from mice fed the SD or WD for 24 or 36 weeks were isolated from Figure S5 J and re-clustered with TotalVI. (K) Distribution of cells in UMAP originating from SD- (purple) or WD- (yellow) fed mice. (L) Proportion of indicated cell types arising from mice fed the SD (purple) or WD (yellow). (M and N) Flow cytometry analysis of indicated cell populations in SD and WD-fed mice (24 weeks). Representative gating strategies (M) and absolute number of indicated populations (N). ∗ p < 0.05, ∗∗ p < 0.01 Student’s t test. Data are from 2 independent experiments with n = 5–6 per diet. (O and P) Top DEGs (O) and DEPs (P) for cell types from Figure 4 H. (Q) Top 25 Murine KC genes as expressed by the human myeloid cell clusters. (R) Mapping of KC signature onto Visium trajectory for healthy (purple) and steatotic (orange) livers. (S) Expression of VSIG4 mRNA within human myeloid cells. (T) Expression of VSIG4 (red) and CD163 (gray, top) or CD169 (gray, bottom) by MICS analysis in healthy human liver. (U) Representative images showing KC location (red) as assessed by MICS analysis in the healthy (left) and steatotic (right) human liver. PV, portal vein; CV, central Vein, dashed line indicates zones of steatosis. (V) Representative image of CD68 and CD163 staining in 10–15-year-old human liver paraffin sections. Image is representative of 6 different patients. (W) In silico gating strategy to isolate distinct myeloid cell populations identified from CITE-seq data. (X) Expression of VSIG4 and FOLR2 by live CD45 + cells also expressing CD14 in indicated human liver biopsies by flow cytometry. Data are representative of 21 biopsy samples analyzed. " width="250" height="auto" />
Nmr Spectrometer Bruker Avance Iv Hd 400, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nmr spectrometer bruker avance iv hd 400/product/Bruker Corporation
Average 90 stars, based on 1 article reviews
nmr spectrometer bruker avance iv hd 400 - by Bioz Stars, 2026-03
90/100 stars
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bandpass butterworth filter  (MathWorks Inc)
90
MathWorks Inc bandpass butterworth filter
Combination of CITE-seq, scRNA-seq, snRNA-seq, and spatial analyses enables generation of a human liver atlas and identification of bona fide human KCs, related to <xref ref-type=Figure 4 (A and B) Top DEGs (A) and DEPs (B) for the cell types from Figure 4 B. (C) Distinct profiles of cells or nuclei within the UMAP depending on isolation protocol used; 152,535 cells from ex vivo digestions and 15,063 nuclei. (D) Proportion of each cell type per patient profiled. (E) Proportion of indicated cell types as a % of total CD45 + cells calculated from ex vivo digested samples per surgery type. Ch; cholecystectomy, Re; resection, GB; gastric bypass. ∗ p < 0.05; one-way ANOVA with Bonferroni post-test. (F) Mapping of Visium UMAP zonation patterns onto tissue sections from patient H35 and H37. (G) Expression of indicated zonation genes in patients H35–H38 assessed by Molecular Cartography. (H and I) Expression of indicated proteins by MICS 100-plex protein analysis in the healthy (H) and steatotic (I) human liver. (J) Murine myeloid cells (cDC1s, cDC2s, Mig. cDCs, Macs, monocytes, and monocyte-derived cells; 42,922 cells) from mice fed the SD or WD for 24 or 36 weeks were isolated from Figure S5 J and re-clustered with TotalVI. (K) Distribution of cells in UMAP originating from SD- (purple) or WD- (yellow) fed mice. (L) Proportion of indicated cell types arising from mice fed the SD (purple) or WD (yellow). (M and N) Flow cytometry analysis of indicated cell populations in SD and WD-fed mice (24 weeks). Representative gating strategies (M) and absolute number of indicated populations (N). ∗ p < 0.05, ∗∗ p < 0.01 Student’s t test. Data are from 2 independent experiments with n = 5–6 per diet. (O and P) Top DEGs (O) and DEPs (P) for cell types from Figure 4 H. (Q) Top 25 Murine KC genes as expressed by the human myeloid cell clusters. (R) Mapping of KC signature onto Visium trajectory for healthy (purple) and steatotic (orange) livers. (S) Expression of VSIG4 mRNA within human myeloid cells. (T) Expression of VSIG4 (red) and CD163 (gray, top) or CD169 (gray, bottom) by MICS analysis in healthy human liver. (U) Representative images showing KC location (red) as assessed by MICS analysis in the healthy (left) and steatotic (right) human liver. PV, portal vein; CV, central Vein, dashed line indicates zones of steatosis. (V) Representative image of CD68 and CD163 staining in 10–15-year-old human liver paraffin sections. Image is representative of 6 different patients. (W) In silico gating strategy to isolate distinct myeloid cell populations identified from CITE-seq data. (X) Expression of VSIG4 and FOLR2 by live CD45 + cells also expressing CD14 in indicated human liver biopsies by flow cytometry. Data are representative of 21 biopsy samples analyzed. " width="250" height="auto" />
Bandpass Butterworth Filter, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bandpass butterworth filter/product/MathWorks Inc
Average 90 stars, based on 1 article reviews
bandpass butterworth filter - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
chiralpak ad  (Daicel Chemical Industries)
90
Daicel Chemical Industries chiralpak ad
Combination of CITE-seq, scRNA-seq, snRNA-seq, and spatial analyses enables generation of a human liver atlas and identification of bona fide human KCs, related to <xref ref-type=Figure 4 (A and B) Top DEGs (A) and DEPs (B) for the cell types from Figure 4 B. (C) Distinct profiles of cells or nuclei within the UMAP depending on isolation protocol used; 152,535 cells from ex vivo digestions and 15,063 nuclei. (D) Proportion of each cell type per patient profiled. (E) Proportion of indicated cell types as a % of total CD45 + cells calculated from ex vivo digested samples per surgery type. Ch; cholecystectomy, Re; resection, GB; gastric bypass. ∗ p < 0.05; one-way ANOVA with Bonferroni post-test. (F) Mapping of Visium UMAP zonation patterns onto tissue sections from patient H35 and H37. (G) Expression of indicated zonation genes in patients H35–H38 assessed by Molecular Cartography. (H and I) Expression of indicated proteins by MICS 100-plex protein analysis in the healthy (H) and steatotic (I) human liver. (J) Murine myeloid cells (cDC1s, cDC2s, Mig. cDCs, Macs, monocytes, and monocyte-derived cells; 42,922 cells) from mice fed the SD or WD for 24 or 36 weeks were isolated from Figure S5 J and re-clustered with TotalVI. (K) Distribution of cells in UMAP originating from SD- (purple) or WD- (yellow) fed mice. (L) Proportion of indicated cell types arising from mice fed the SD (purple) or WD (yellow). (M and N) Flow cytometry analysis of indicated cell populations in SD and WD-fed mice (24 weeks). Representative gating strategies (M) and absolute number of indicated populations (N). ∗ p < 0.05, ∗∗ p < 0.01 Student’s t test. Data are from 2 independent experiments with n = 5–6 per diet. (O and P) Top DEGs (O) and DEPs (P) for cell types from Figure 4 H. (Q) Top 25 Murine KC genes as expressed by the human myeloid cell clusters. (R) Mapping of KC signature onto Visium trajectory for healthy (purple) and steatotic (orange) livers. (S) Expression of VSIG4 mRNA within human myeloid cells. (T) Expression of VSIG4 (red) and CD163 (gray, top) or CD169 (gray, bottom) by MICS analysis in healthy human liver. (U) Representative images showing KC location (red) as assessed by MICS analysis in the healthy (left) and steatotic (right) human liver. PV, portal vein; CV, central Vein, dashed line indicates zones of steatosis. (V) Representative image of CD68 and CD163 staining in 10–15-year-old human liver paraffin sections. Image is representative of 6 different patients. (W) In silico gating strategy to isolate distinct myeloid cell populations identified from CITE-seq data. (X) Expression of VSIG4 and FOLR2 by live CD45 + cells also expressing CD14 in indicated human liver biopsies by flow cytometry. Data are representative of 21 biopsy samples analyzed. " width="250" height="auto" />
Chiralpak Ad, supplied by Daicel Chemical Industries, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/chiralpak ad/product/Daicel Chemical Industries
Average 90 stars, based on 1 article reviews
chiralpak ad - by Bioz Stars, 2026-03
90/100 stars
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v2024.12.1 + 563  (RStudio)
90
RStudio v2024.12.1 + 563
Combination of CITE-seq, scRNA-seq, snRNA-seq, and spatial analyses enables generation of a human liver atlas and identification of bona fide human KCs, related to <xref ref-type=Figure 4 (A and B) Top DEGs (A) and DEPs (B) for the cell types from Figure 4 B. (C) Distinct profiles of cells or nuclei within the UMAP depending on isolation protocol used; 152,535 cells from ex vivo digestions and 15,063 nuclei. (D) Proportion of each cell type per patient profiled. (E) Proportion of indicated cell types as a % of total CD45 + cells calculated from ex vivo digested samples per surgery type. Ch; cholecystectomy, Re; resection, GB; gastric bypass. ∗ p < 0.05; one-way ANOVA with Bonferroni post-test. (F) Mapping of Visium UMAP zonation patterns onto tissue sections from patient H35 and H37. (G) Expression of indicated zonation genes in patients H35–H38 assessed by Molecular Cartography. (H and I) Expression of indicated proteins by MICS 100-plex protein analysis in the healthy (H) and steatotic (I) human liver. (J) Murine myeloid cells (cDC1s, cDC2s, Mig. cDCs, Macs, monocytes, and monocyte-derived cells; 42,922 cells) from mice fed the SD or WD for 24 or 36 weeks were isolated from Figure S5 J and re-clustered with TotalVI. (K) Distribution of cells in UMAP originating from SD- (purple) or WD- (yellow) fed mice. (L) Proportion of indicated cell types arising from mice fed the SD (purple) or WD (yellow). (M and N) Flow cytometry analysis of indicated cell populations in SD and WD-fed mice (24 weeks). Representative gating strategies (M) and absolute number of indicated populations (N). ∗ p < 0.05, ∗∗ p < 0.01 Student’s t test. Data are from 2 independent experiments with n = 5–6 per diet. (O and P) Top DEGs (O) and DEPs (P) for cell types from Figure 4 H. (Q) Top 25 Murine KC genes as expressed by the human myeloid cell clusters. (R) Mapping of KC signature onto Visium trajectory for healthy (purple) and steatotic (orange) livers. (S) Expression of VSIG4 mRNA within human myeloid cells. (T) Expression of VSIG4 (red) and CD163 (gray, top) or CD169 (gray, bottom) by MICS analysis in healthy human liver. (U) Representative images showing KC location (red) as assessed by MICS analysis in the healthy (left) and steatotic (right) human liver. PV, portal vein; CV, central Vein, dashed line indicates zones of steatosis. (V) Representative image of CD68 and CD163 staining in 10–15-year-old human liver paraffin sections. Image is representative of 6 different patients. (W) In silico gating strategy to isolate distinct myeloid cell populations identified from CITE-seq data. (X) Expression of VSIG4 and FOLR2 by live CD45 + cells also expressing CD14 in indicated human liver biopsies by flow cytometry. Data are representative of 21 biopsy samples analyzed. " width="250" height="auto" />
V2024.12.1 + 563, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/v2024.12.1 + 563/product/RStudio
Average 90 stars, based on 1 article reviews
v2024.12.1 + 563 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
pfizer vaccination  (Pfizer Inc)
90
Pfizer Inc pfizer vaccination
Demographic characteristics difference between patients with the Sinopharm and Pfizer vaccinations
Pfizer Vaccination, supplied by Pfizer Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pfizer vaccination/product/Pfizer Inc
Average 90 stars, based on 1 article reviews
pfizer vaccination - by Bioz Stars, 2026-03
90/100 stars
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phycoerythrin (pe) conjugated antibodies hla-dr  (Thermo Fisher)
90
Thermo Fisher phycoerythrin (pe) conjugated antibodies hla-dr
Demographic characteristics difference between patients with the Sinopharm and Pfizer vaccinations
Phycoerythrin (Pe) Conjugated Antibodies Hla Dr, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/phycoerythrin (pe) conjugated antibodies hla-dr/product/Thermo Fisher
Average 90 stars, based on 1 article reviews
phycoerythrin (pe) conjugated antibodies hla-dr - by Bioz Stars, 2026-03
90/100 stars
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ht1080 fibrosarcoma cells  (ATCC)
98
ATCC ht1080 fibrosarcoma cells
Demographic characteristics difference between patients with the Sinopharm and Pfizer vaccinations
Ht1080 Fibrosarcoma Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ht1080 fibrosarcoma cells/product/ATCC
Average 98 stars, based on 1 article reviews
ht1080 fibrosarcoma cells - by Bioz Stars, 2026-03
98/100 stars
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121 87 1 pulmonary 65 50 4 40 61 5 25  (ATCC)
93
ATCC 121 87 1 pulmonary 65 50 4 40 61 5 25
Demographic characteristics difference between patients with the Sinopharm and Pfizer vaccinations
121 87 1 Pulmonary 65 50 4 40 61 5 25, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/121 87 1 pulmonary 65 50 4 40 61 5 25/product/ATCC
Average 93 stars, based on 1 article reviews
121 87 1 pulmonary 65 50 4 40 61 5 25 - by Bioz Stars, 2026-03
93/100 stars
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gene exp afp mm00431715 m1  (Thermo Fisher)
97
Thermo Fisher gene exp afp mm00431715 m1
Demographic characteristics difference between patients with the Sinopharm and Pfizer vaccinations
Gene Exp Afp Mm00431715 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gene exp afp mm00431715 m1/product/Thermo Fisher
Average 97 stars, based on 1 article reviews
gene exp afp mm00431715 m1 - by Bioz Stars, 2026-03
97/100 stars
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Image Search Results


Combination of CITE-seq, scRNA-seq, snRNA-seq, and spatial analyses enables generation of a human liver atlas and identification of bona fide human KCs, related to <xref ref-type=Figure 4 (A and B) Top DEGs (A) and DEPs (B) for the cell types from Figure 4 B. (C) Distinct profiles of cells or nuclei within the UMAP depending on isolation protocol used; 152,535 cells from ex vivo digestions and 15,063 nuclei. (D) Proportion of each cell type per patient profiled. (E) Proportion of indicated cell types as a % of total CD45 + cells calculated from ex vivo digested samples per surgery type. Ch; cholecystectomy, Re; resection, GB; gastric bypass. ∗ p < 0.05; one-way ANOVA with Bonferroni post-test. (F) Mapping of Visium UMAP zonation patterns onto tissue sections from patient H35 and H37. (G) Expression of indicated zonation genes in patients H35–H38 assessed by Molecular Cartography. (H and I) Expression of indicated proteins by MICS 100-plex protein analysis in the healthy (H) and steatotic (I) human liver. (J) Murine myeloid cells (cDC1s, cDC2s, Mig. cDCs, Macs, monocytes, and monocyte-derived cells; 42,922 cells) from mice fed the SD or WD for 24 or 36 weeks were isolated from Figure S5 J and re-clustered with TotalVI. (K) Distribution of cells in UMAP originating from SD- (purple) or WD- (yellow) fed mice. (L) Proportion of indicated cell types arising from mice fed the SD (purple) or WD (yellow). (M and N) Flow cytometry analysis of indicated cell populations in SD and WD-fed mice (24 weeks). Representative gating strategies (M) and absolute number of indicated populations (N). ∗ p < 0.05, ∗∗ p < 0.01 Student’s t test. Data are from 2 independent experiments with n = 5–6 per diet. (O and P) Top DEGs (O) and DEPs (P) for cell types from Figure 4 H. (Q) Top 25 Murine KC genes as expressed by the human myeloid cell clusters. (R) Mapping of KC signature onto Visium trajectory for healthy (purple) and steatotic (orange) livers. (S) Expression of VSIG4 mRNA within human myeloid cells. (T) Expression of VSIG4 (red) and CD163 (gray, top) or CD169 (gray, bottom) by MICS analysis in healthy human liver. (U) Representative images showing KC location (red) as assessed by MICS analysis in the healthy (left) and steatotic (right) human liver. PV, portal vein; CV, central Vein, dashed line indicates zones of steatosis. (V) Representative image of CD68 and CD163 staining in 10–15-year-old human liver paraffin sections. Image is representative of 6 different patients. (W) In silico gating strategy to isolate distinct myeloid cell populations identified from CITE-seq data. (X) Expression of VSIG4 and FOLR2 by live CD45 + cells also expressing CD14 in indicated human liver biopsies by flow cytometry. Data are representative of 21 biopsy samples analyzed. " width="100%" height="100%">

Journal: Cell

Article Title: Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

doi: 10.1016/j.cell.2021.12.018

Figure Lengend Snippet: Combination of CITE-seq, scRNA-seq, snRNA-seq, and spatial analyses enables generation of a human liver atlas and identification of bona fide human KCs, related to Figure 4 (A and B) Top DEGs (A) and DEPs (B) for the cell types from Figure 4 B. (C) Distinct profiles of cells or nuclei within the UMAP depending on isolation protocol used; 152,535 cells from ex vivo digestions and 15,063 nuclei. (D) Proportion of each cell type per patient profiled. (E) Proportion of indicated cell types as a % of total CD45 + cells calculated from ex vivo digested samples per surgery type. Ch; cholecystectomy, Re; resection, GB; gastric bypass. ∗ p < 0.05; one-way ANOVA with Bonferroni post-test. (F) Mapping of Visium UMAP zonation patterns onto tissue sections from patient H35 and H37. (G) Expression of indicated zonation genes in patients H35–H38 assessed by Molecular Cartography. (H and I) Expression of indicated proteins by MICS 100-plex protein analysis in the healthy (H) and steatotic (I) human liver. (J) Murine myeloid cells (cDC1s, cDC2s, Mig. cDCs, Macs, monocytes, and monocyte-derived cells; 42,922 cells) from mice fed the SD or WD for 24 or 36 weeks were isolated from Figure S5 J and re-clustered with TotalVI. (K) Distribution of cells in UMAP originating from SD- (purple) or WD- (yellow) fed mice. (L) Proportion of indicated cell types arising from mice fed the SD (purple) or WD (yellow). (M and N) Flow cytometry analysis of indicated cell populations in SD and WD-fed mice (24 weeks). Representative gating strategies (M) and absolute number of indicated populations (N). ∗ p < 0.05, ∗∗ p < 0.01 Student’s t test. Data are from 2 independent experiments with n = 5–6 per diet. (O and P) Top DEGs (O) and DEPs (P) for cell types from Figure 4 H. (Q) Top 25 Murine KC genes as expressed by the human myeloid cell clusters. (R) Mapping of KC signature onto Visium trajectory for healthy (purple) and steatotic (orange) livers. (S) Expression of VSIG4 mRNA within human myeloid cells. (T) Expression of VSIG4 (red) and CD163 (gray, top) or CD169 (gray, bottom) by MICS analysis in healthy human liver. (U) Representative images showing KC location (red) as assessed by MICS analysis in the healthy (left) and steatotic (right) human liver. PV, portal vein; CV, central Vein, dashed line indicates zones of steatosis. (V) Representative image of CD68 and CD163 staining in 10–15-year-old human liver paraffin sections. Image is representative of 6 different patients. (W) In silico gating strategy to isolate distinct myeloid cell populations identified from CITE-seq data. (X) Expression of VSIG4 and FOLR2 by live CD45 + cells also expressing CD14 in indicated human liver biopsies by flow cytometry. Data are representative of 21 biopsy samples analyzed.

Article Snippet: Anti-Human CD163 (REA406) PE , Miltenyi Biotec , 130-121-316; RRID: AB_2857545.

Techniques: Isolation, Ex Vivo, Expressing, Derivative Assay, Flow Cytometry, Staining, In Silico

Journal: Cell

Article Title: Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

doi: 10.1016/j.cell.2021.12.018

Figure Lengend Snippet:

Article Snippet: Anti-Human CD163 (REA406) PE , Miltenyi Biotec , 130-121-316; RRID: AB_2857545.

Techniques: Purification, Recombinant, Staining, cDNA Synthesis, Gene Expression, Software, Microscopy

Demographic characteristics difference between patients with the Sinopharm and Pfizer vaccinations

Journal: International Journal of Gynaecology and Obstetrics

Article Title: COVID ‐19 vaccinations in pregnancy: Save mother and baby from COVID ‐19 pandemic

doi: 10.1002/ijgo.14532

Figure Lengend Snippet: Demographic characteristics difference between patients with the Sinopharm and Pfizer vaccinations

Article Snippet: Antibody intervals frequency of Sinopharm vaccination group from the second dose were highest within 61 to 71 and 111 to 121 days, whereas intervals from Pfizer vaccination were highest within 34 to 44 and 54 to 64 days as shown in Figure .

Techniques:

(a) Interval frequencies of Sinopharm vaccination. (b) Interval frequencies of Pfizer vaccination.

Journal: International Journal of Gynaecology and Obstetrics

Article Title: COVID ‐19 vaccinations in pregnancy: Save mother and baby from COVID ‐19 pandemic

doi: 10.1002/ijgo.14532

Figure Lengend Snippet: (a) Interval frequencies of Sinopharm vaccination. (b) Interval frequencies of Pfizer vaccination.

Article Snippet: Antibody intervals frequency of Sinopharm vaccination group from the second dose were highest within 61 to 71 and 111 to 121 days, whereas intervals from Pfizer vaccination were highest within 34 to 44 and 54 to 64 days as shown in Figure .

Techniques:

Correlation between maternal factors with Sinopharm and Pfizer vaccinations of mother and cord blood antibodies

Journal: International Journal of Gynaecology and Obstetrics

Article Title: COVID ‐19 vaccinations in pregnancy: Save mother and baby from COVID ‐19 pandemic

doi: 10.1002/ijgo.14532

Figure Lengend Snippet: Correlation between maternal factors with Sinopharm and Pfizer vaccinations of mother and cord blood antibodies

Article Snippet: Antibody intervals frequency of Sinopharm vaccination group from the second dose were highest within 61 to 71 and 111 to 121 days, whereas intervals from Pfizer vaccination were highest within 34 to 44 and 54 to 64 days as shown in Figure .

Techniques:

Correlation between maternal factors with Sinopharm and Pfizer vaccinations of antibodies transfer ratio

Journal: International Journal of Gynaecology and Obstetrics

Article Title: COVID ‐19 vaccinations in pregnancy: Save mother and baby from COVID ‐19 pandemic

doi: 10.1002/ijgo.14532

Figure Lengend Snippet: Correlation between maternal factors with Sinopharm and Pfizer vaccinations of antibodies transfer ratio

Article Snippet: Antibody intervals frequency of Sinopharm vaccination group from the second dose were highest within 61 to 71 and 111 to 121 days, whereas intervals from Pfizer vaccination were highest within 34 to 44 and 54 to 64 days as shown in Figure .

Techniques:

Frequencies and association of maternal factors with antibody transfer ratios of Sinopharm and Pfizer vaccinations

Journal: International Journal of Gynaecology and Obstetrics

Article Title: COVID ‐19 vaccinations in pregnancy: Save mother and baby from COVID ‐19 pandemic

doi: 10.1002/ijgo.14532

Figure Lengend Snippet: Frequencies and association of maternal factors with antibody transfer ratios of Sinopharm and Pfizer vaccinations

Article Snippet: Antibody intervals frequency of Sinopharm vaccination group from the second dose were highest within 61 to 71 and 111 to 121 days, whereas intervals from Pfizer vaccination were highest within 34 to 44 and 54 to 64 days as shown in Figure .

Techniques: